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Table 2 Laboratory information of the training set on PICU admission

From: Development and validation of a nomogram to predict the risk of sepsis-associated encephalopathy for septic patients in PICU: a multicenter retrospective cohort study

Characteristics

Total

(n = 251)

Non-SAE group

(n = 161)

SAE group

(n = 90)

P value

WBC (× 109/L)

11.1 (6.1, 20.3)

11.2 (6.4, 20.2)

10.5 (5.5, 21.2)

0.738

PLT (× 109/L)

273 (127, 414)

300 (157, 430)

220.5 (74, 397.8)

0.017

HB (g/L)

103.7 ± 26.1

106.1 ± 23.9

99.3 ± 29.2

0.059

ALT (U/L)

20 (11, 46)

18 (10, 44)

24.5 (13, 59.2)

0.015

TBIL (umol/L)

6.7 (4.3, 11.4)

6.1 (3.8, 10.3)

8.1 (5.1, 16.3)

0.002

Albumin (g/L)

36.9 (31.8, 40.9)

37.7 (33.8, 40.9)

35 (29.1, 41)

0.018

CK-MB (mg/L)

1.5 (0.8, 3.2)

1.2 (0.6, 2.1)

2.5 (1.5, 7.3)

< 0.001

Scr (umol/L)

30 (23, 40.5)

28 (23, 38)

33 (23.2, 53.8)

0.006

BUN (mmol/L)

3.4 (2.5, 4.6)

3.2 (2.4, 3.9)

4 (2.9, 6.1)

< 0.001

LDH (U/L)

384 (270.5, 659)

332 (251, 547)

459.5 (338.8, 1050.2)

< 0.001

Na (mmol/L)

137 (134, 139)

137 (134, 139)

137 (132.2, 139)

0.494

K (mmol/L)

4.2 ± 0.6

4.2 ± 0.6

4.3 ± 0.7

0.263

Fib (g/L)

3 (2.3, 4.1)

3.1 (2.5, 4.1)

2.7 (1.6, 4.1)

0.007

INR

1.2 (1.1, 1.3)

1.2 (1.1, 1.3)

1.2 (1.1, 1.3)

0.157

PT (s)

14 (12.9, 15.6)

13.9 (12.8, 14.9)

14.4 (13, 16.7)

0.006

APTT (s)

36.6 (33.3, 39.7)

35.6 (32, 38.1)

38.8 (35.6, 44)

< 0.001

D-dimer (ug/mL)

1.6 (0.7, 4.8)

1.5 (0.7, 3.8)

1.7 (0.9, 12.4)

0.163

BNP (ng/L)

256 (120, 545)

245 (120, 480)

292.2 (120, 787.2)

0.252

CRP (mg/L)

33.1 (7, 96.9)

34.7 (7.4, 88.9)

31.6 (3.4, 106)

0.464

PCT (ug/L)

0.4 (0.2, 1.4)

0.4 (0.2, 1.3)

0.3 (0.1, 1.5)

0.967

Lactate (mmol/L)

1.4 (1, 2.3)

1.4 (1, 2)

1.6 (1.1, 2.6)

0.030

PH

7.4 (7.4, 7.5)

7.4 (7.4, 7.5)

7.4 (7.4, 7.5)

0.348

PaO2 (mmHg)

83 (74, 98)

85 (78, 98)

81 (65, 97)

0.022

PaCO2 (mmHg)

34 (28, 38)

33 (27, 37)

36 (31.2, 42)

< 0.001

SaO2 (%)

97.9 (95.2, 99)

98 (95.3, 99.1)

97.4 (95.4, 98.9)

0.281

Glucose (mmol/L)

5.8 (5.1, 7.2)

5.7 (5, 6.8)

6.3 (5.2, 8.5)

0.040

PCIS

92 (87, 96)

94 (90, 96)

90 (80.5, 96)

< 0.001

  1. WBC: white blood cell; PLT: platelet; HB: hemoglobin; ALT: alanine transaminase; TBIL: total bilirubin; CK-MB: creatine kinase-MB; Scr: serum creatinine; BUN: blood urea nitrogen; LDH: lactic dehydrogenase; Na: serum sodium; K: serum potassium; Fib: fibrinogen; INR: international normalized ratio; PT: prothrombin time; APTT: activated partial thromboplastin time; BNP: brain natriuretic peptide; CRP: C reactive protein; PCT: procalcitonin; PaO2: arterial oxygen partial pressure; PaCO2: arterial partial pressure of carbon dioxide; SaO2: arterial oxygen saturation; PCIS: pediatric critical illness score