Table 1 Baseline and clinical characteristics of the training set
Characteristics | Total (n = 251) | Non-SAE group (n = 161) | SAE group (n = 90) | P value |
|---|---|---|---|---|
Age (month) | 48 (15.5, 95) | 48 (18, 94) | 46.5 (8.2, 99) | 0.773 |
Gender (male, %) | 137 (54.6) | 84 (52.2) | 53 (58.9) | 0.372 |
Vital signs | Â | Â | Â | Â |
 HR (beats/min) | 120 (102.5, 139.5) | 115 (102, 131) | 126.5 (109.2, 149) | 0.004 |
 RR (breaths/min) | 26 (23, 32) | 25 (22, 30) | 30 (25, 40) | < 0.001 |
 SBP (mmHg) | 99 (85.5, 115) | 97 (85, 112) | 103.5 (86, 115.8) | 0.281 |
 DBP (mmHg) | 57 (49, 68) | 57 (50, 67) | 60 (47.2, 69.8) | 0.704 |
Temperature > 38 ℃, n (%) | 92 (36.7) | 58 (36) | 34 (37.8) | 0.889 |
Suspected infection focus, n (%) | Â | Â | Â | 0.425 |
 Respiratory infection | 120 (47.8) | 74 (46) | 46 (51.1) |  |
 Blood infection | 37 (14.7) | 23 (14.3) | 14 (15.6) |  |
 Urinary tract infection | 4 (1.6) | 2 (1.2) | 2 (2.2) |  |
 Intra-abdominal infection | 18 (7.2) | 15 (9.3) | 3 (3.3) |  |
 Other or unknown | 72 (28.7) | 47 (29.2) | 25 (27.8) |  |
Blood culture-positive, n (%) | 40 (15.9) | 22 (13.7) | 18 (20) | 0.256 |
Microorganisms, n (%) | 83 (33.1) | 48 (29.8) | 35 (38.9) | 0.185 |
 Gram-positive | 35 (13.9) | 25 (15.5) | 10 (11.1) | 0.436 |
 Gram-negative | 29 (11.6) | 14 (8.7) | 15 (16.7) | 0.091 |
 Fungus | 8 (3.2) | 4 (2.5) | 4 (4.4) | 0.463 |
 Multiple infection (two or more) | 18 (7.2) | 9 (5.6) | 9 (10) | 0.297 |
Vasopressor use during PICU stay time, n (%) | 36 (14.3) | 3 (1.9) | 33 (36.7) | < 0.001 |
Advanced life support during PICU stay time | Â | Â | Â | Â |
 Mechanical ventilation, n (%) | 35 (13.9) | 5 (3.1) | 30 (33.3) | < 0.001 |
 Renal replacement therapy, n (%) | 26 (10.4) | 13 (8.1) | 13 (14.4) | 0.170 |
Outcome | Â | Â | Â | Â |
 Multi-organ dysfunction (two or more), n (%) | 127 (50.6) | 48 (29.8) | 79 (87.8) | < 0.001 |
 Septic shock, n (%) | 18 (7.2) | 9 (5.6) | 9 (10) | 0.297 |
 Hospital stay time (days) | 12 (7, 21.5) | 12 (7, 21) | 12 (8, 23) | 0.717 |
 PICU stay time (days) | 9 (4, 15) | 9 (5, 15) | 9 (3, 17) | 0.892 |
 In-hospital mortality, n (%) | 32 (12.7) | 0 (0) | 32 (35.6) | < 0.001 |