From: Chest CT findings in severe acute respiratory distress syndrome requiring V-V ECMO: J-CARVE registry
 | All patients (n = 582) | Survived (n = 407) | Died (n = 175) | p-value |
---|---|---|---|---|
Mechanical ventilation settings during ECMO support | Â | Â | Â | Â |
Mechanical ventilator mode | Â | Â | Â | 0.90 |
 Pressure control, n (%) | 557 (95.9) | 391 (96.1) | 166 (95.4) |  |
 Volume control, n (%) | 13 (2.2) | 9 (2.2) | 4 (2.3) |  |
PEEP during 1–3 days, cmH2Oa | 10.0 ± 3.4 | 10.1 ± 3.4 | 9.7 ± 3.3 | 0.24 |
Dynamic driving pressure during 1–3 days, cmH2Ob | 10.0 ± 5.2 | 10.3 ± 5.5 | 9.5 ± 4.4 | 0.06 |
PEEP during 4–7 days, cmH2Oc | 10.3 ± 5.2 | 10.4 ± 5.9 | 9.9 ± 3.0 | 0.23 |
Dynamic driving pressure during 4–7 days, cmH2Od | 10.0 ± 5.0 | 10.4 ± 5.4 | 9.2 ± 3.8 | 0.016 |
ECMO setting | Â | Â | Â | Â |
 Blood flow, L/mine | 3.9 ± 0.7 | 3.9 ± 0.7 | 3.9 ± 0.7 | 0.28 |
 Sweep gas, L/minf | 3.7 ± 1.9 | 3.8 ± 1.9 | 3.7 ± 2.0 | 0.84 |
 FdO2 | 1.0 (1.0–1.0) | 1.0 (1.0–1.0) | 1.0 (1.0–1.0) |  > 0.99 |
Cannulation site (drainage-return cannula) | Â | Â | Â | 0.30 |
 Jugular–femoral, n (%) | 315 (54.1) | 229 (56.3) | 86 (49.1) |  |
 Femoral–jugular, n (%) | 236 (40.6) | 155 (38.1) | 81 (46.3) |  |
 Femoral–femoral, n (%) | 25 (4.3) | 19 (4.7) | 6 (3.4) |  |
Treatment during ECMO support | Â | Â | Â | Â |
Corticosteroid use within 2Â weeks, n (%)g | 399 (68.7) | 269 (66.1) | 130 (74.7) | 0.038 |
Neuromuscular blocker use within 48Â h, n (%)h | 325 (56.1) | 231 (56.9) | 94 (54.3) | 0.59 |
Prone positioning within 2Â weeks, n (%)i | 147 (25.4) | 102 (25.2) | 45 (26.0) | 0.83 |
Duration of ECMO run, daysj | 11.0 (7.0–19.0) | 9.5 (7.0–14.0) | 19.0 (9.0–36.0) |  < 0.001 |
Re-cannulation of ECMO, n (%)k | 22 (3.8) | 11 (2.7) | 11 (6.3) | 0.046 |