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Table 2 Baseline characteristics of all participants after V-V ECMO instauration

From: Chest CT findings in severe acute respiratory distress syndrome requiring V-V ECMO: J-CARVE registry

 

All patients

(n = 582)

Survived

(n = 407)

Died

(n = 175)

p-value

Mechanical ventilation settings during ECMO support

    

Mechanical ventilator mode

   

0.90

 Pressure control, n (%)

557 (95.9)

391 (96.1)

166 (95.4)

 

 Volume control, n (%)

13 (2.2)

9 (2.2)

4 (2.3)

 

PEEP during 1–3 days, cmH2Oa

10.0 ± 3.4

10.1 ± 3.4

9.7 ± 3.3

0.24

Dynamic driving pressure during 1–3 days, cmH2Ob

10.0 ± 5.2

10.3 ± 5.5

9.5 ± 4.4

0.06

PEEP during 4–7 days, cmH2Oc

10.3 ± 5.2

10.4 ± 5.9

9.9 ± 3.0

0.23

Dynamic driving pressure during 4–7 days, cmH2Od

10.0 ± 5.0

10.4 ± 5.4

9.2 ± 3.8

0.016

ECMO setting

    

 Blood flow, L/mine

3.9 ± 0.7

3.9 ± 0.7

3.9 ± 0.7

0.28

 Sweep gas, L/minf

3.7 ± 1.9

3.8 ± 1.9

3.7 ± 2.0

0.84

 FdO2

1.0 (1.0–1.0)

1.0 (1.0–1.0)

1.0 (1.0–1.0)

 > 0.99

Cannulation site (drainage-return cannula)

   

0.30

 Jugular–femoral, n (%)

315 (54.1)

229 (56.3)

86 (49.1)

 

 Femoral–jugular, n (%)

236 (40.6)

155 (38.1)

81 (46.3)

 

 Femoral–femoral, n (%)

25 (4.3)

19 (4.7)

6 (3.4)

 

Treatment during ECMO support

    

Corticosteroid use within 2 weeks, n (%)g

399 (68.7)

269 (66.1)

130 (74.7)

0.038

Neuromuscular blocker use within 48 h, n (%)h

325 (56.1)

231 (56.9)

94 (54.3)

0.59

Prone positioning within 2 weeks, n (%)i

147 (25.4)

102 (25.2)

45 (26.0)

0.83

Duration of ECMO run, daysj

11.0 (7.0–19.0)

9.5 (7.0–14.0)

19.0 (9.0–36.0)

 < 0.001

Re-cannulation of ECMO, n (%)k

22 (3.8)

11 (2.7)

11 (6.3)

0.046

  1. Data are presented as the median and interquartile range (25–75% percentile), mean ± standard deviation, or absolute frequency with percentage
  2. ECMO: extracorporeal membrane oxygenation; FdO2: fraction of oxygen delivered from the blender; PEEP: positive end-expiratory pressure
  3. aMissing values = 4
  4. bMissing values = 16
  5. cMissing values = 34
  6. dMissing values = 44
  7. eMissing values = 5
  8. fMissing values = 8
  9. gMissing value = 1
  10. hMissing values = 2
  11. iMissing values = 4
  12. jMissing values = 5
  13. kMissing values = 2