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Table 5 Linear mixed-effects regression for desphospho-uncarboxylated matrix Gla protein (dp-ucMGP) levels (pmol/L) and pulmonary embolism (PE) in the intensive care unit (ICU)

From: Higher levels of circulating desphospho-uncarboxylated matrix Gla protein over time are associated with worse survival: the prospective Maastricht Intensive Care COVID cohort

Model

dp-ucMGP (pmol/L)

CI (95%) (pmol/L)

p-value

Model 1: crude

 No pulmonary embolism (reference)

Ref.

Ref.

Ref.

 Presence of pulmonary embolism

− 124

− 301–54

0.219

Model 2: model 1 + age + gender + APACHE II score

 No pulmonary embolism (reference)

Ref.

Ref.

Ref.

 Presence of pulmonary embolism

− 98

− 274–77

0.274

Model 3: model 2 + c-reactive protein (at ETI) + creatinine (at ETI) + history of coumarin use

 No pulmonary embolism (reference)

Ref.

Ref.

Ref.

 Presence of pulmonary embolism

− 31

− 195–133

0.712

  1. CI confidence interval, APACHE II score Acute Physiology and Chronic Health Evaluation II score, ETI endotracheal intubation, Group differences were calculated compared to the reference, p-value < 0.05