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Table 4 Linear mixed-effects regression for desphospho-uncarboxylated matrix Gla protein (dp-ucMGP) levels (pmol/L) and intensive care unit (ICU) mortality

From: Higher levels of circulating desphospho-uncarboxylated matrix Gla protein over time are associated with worse survival: the prospective Maastricht Intensive Care COVID cohort

Model

dp-ucMGP (pmol/L)

CI (95%) (pmol/L)

p-value

Model 1: crude

 ICU survivors (reference)

Ref.

Ref.

Ref.

 ICU non-survivors

159

− 2–321

0.054

Model 2: model 1 + age + gender + APACHE II score

 ICU survivors (reference)

Ref.

Ref.

Ref.

 ICU non-survivors

167

4–332

0.047

Model 3: model 2 + c-reactive protein (at ETI) + creatinine (at ETI) + history of coumarin use

 ICU survivors (reference)

Ref.

Ref.

Ref.

 ICU non-survivors

199

50–346

0.010

Model 4: model 2 + CAC score

   

 ICU survivors (reference)

Ref.

Ref.

Ref.

 ICU non-survivors

213

3–422

0.051

  1. CI confidence interval, APACHE II score Acute Physiology, and Chronic Health Evaluation II score, CAC score Coronary artery calcifications scores, ETI endotracheal intubation, Group differences were calculated compared to the reference, p-value < 0.05