Higher levels of circulating desphospho-uncarboxylated matrix Gla protein over time are associated with worse survival: the prospective Maastricht Intensive Care COVID cohort

Table 2 Number of COVID-19 patients, citrate sampling sample dates, desphospho-uncarboxylated matrix Gla protein (dp-ucMGP) levels (pmol/L), routine laboratory measurements, and Sequential Organ Failure Assessment (SOFA) scores per week of intensive care unit (ICU) admission starting from endotracheal intubation for ICU survivors and ICU non-survivors

Variables	0		1		2		3		p-value
Variables	Survivor	Non-survivor	Survivor	Non-survivor	Survivor	Non-survivor	Survivor	Non-survivor	Survivor	Non-survivor
Serum Samples, n	48	41	40	36	25	24	18	7	NA	NA
Number of days (days), median [IQR]	4 [2–6]	5 [3–6]	10 [9–11]	10 [9–12]	16 [15–19]	18 [16–19]	24 [23–27]	24 [22–26]	NA	NA
dp-ucMGP (pmol/L), median [IQR]	821 [649-1022]	920 [714-1227]	724 [609-874]	835 [642-998]	865 [697-1118]	928 [679-1134]	887 [686-1087]	850 [767-1180]	0.070	0.472
SOFA score, median [IQR]	10 [7–11]	11 [10–12]	8 [7–11]	12 [10–12]	7 [7–10]	12 [11, 12]	8 [7–12]	12 [10–12]	0.472	0.805

IQR interquartile range, NA not applicable, Kruskal–Wallis test was used for non-parametric data, p-value < 0.05

ISSN: 2052-0492