Table 2 Mechanical ventilation data and outcomes
|  | All patients (n = 6251) | Stratification by first day P/F ratio | |||
|---|---|---|---|---|---|
 > 300 mm Hg (n = 2448) |  > 200 to ≤ 300 mm Hg (n = 958) |  > 100 to ≤ 200 mm Hg (n = 1736) |  ≤ 100 mm Hg (n = 1109) | ||
P/F ratio (mmHg) | 162 (101, 257) | 375 (333, 433) | 244 (220, 270) | 143 (120, 168) | 73 (59, 86) |
Peak inspiratory pressure (cm H2O) | 19.7 (16.2, 23.6) | 17.7 (14.7, 21.6) | 18.7 (15.9, 22.2) | 20.6 (17.6, 24.3) | 23.1 (19.7, 26.7) |
Positive end-expiratory pressure (cm H2O) | 6.1 (5, 8.4) | 5 (4.9, 6.7) | 5.5 (4.9, 7) | 7 (5.4, 8.9) | 8.8 (6.9, 11.2) |
Measured respiratory rate (min−1) | 20.7 (18, 23.5) | 19.9 (17.2, 22.5) | 19.9 (17.6, 22.5) | 21.1 (18.4, 23.9) | 22.8 (19.8, 25.7) |
Tidal volume (mL) | 460 (404, 518) | 455 (399, 512) | 461 (405, 521) | 468 (410, 523) | 457 (400, 521) |
Tidal volume per predicted body weight (mL/kg) | 7.0 (6.3, 7.9) | 7.0 (6.3, 7.9) | 7.1 (6.3, 8.0) | 7.1 (6.3, 7.9) | 6.9 (6.2, 7.7) |
Total dynamic mechanical ventilation intensity (J) | 105,214 (65,091, 184,169) | 84,269 (55,780, 142,501) | 89,756 (60,396, 151,851) | 116,859 (74,919, 196,094) | 162,460 (96,696, 274,257) |
Averaged dynamic mechanical power (J/min) | 11.8 (9, 15.8) | 10 (8, 13) | 10.8 (8.8, 13.7) | 13.1 (10.1, 16.9) | 15.9 (12.1, 20.6) |
SaO2 (%) | 97 (95, 98) | 98 (97, 99) | 97 (96, 98) | 96 (94, 98) | 96 (92, 98) |
SpO2 (%) | 98 (95, 100) | 100 (97, 100) | 99 (97, 100) | 97 (95, 99) | 96 (93, 99) |
PaO2 (mmHg) | 106 (80, 149) | 151 (103, 200) | 119 (101, 156) | 95 (77, 124) | 83 (63, 107) |
PaCO2 (mmHg) | 39 (34, 45) | 37 (32, 43) | 39 (34, 44) | 39 (34, 45) | 41 (36, 50) |
Lactate (mmol/L) | 1.7 (1.2, 2.8) | 1.5 (1.1, 2.3) | 1.6 (1.1, 2.5) | 1.8 (1.2, 2.9) | 2.1 (1.4, 3.6) |
Outcomes | |||||
 ICU mortality at 28 days | 1857 (29.7%) | 717 (29.3%) | 261 (27.2%) | 499 (28.7%) | 380 (34.3%) |
 ICU mortality | 1588 (25.4%) | 567 (23.2%) | 230 (24%) | 446 (25.7%) | 345 (31.1%) |
 Duration of mechanical ventilation (days) | 6 (4.2, 9.5) | 5.7 (4, 8.9) | 5.7 (3.9, 9) | 6.1 (4.2, 9.5) | 7.1 (4.7, 11.1) |
 Length of ICU stay (days) | 9.9 (6.7, 15.4) | 9.9 (6.7, 15.4) | 9.4 (6.3, 14.9) | 9.7 (6.7, 15) | 10.9 (7.1, 16.6) |