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Table 2 Results of doubly robust estimation

From: Prognostic value of oxygen saturation index trajectory phenotypes on ICU mortality in mechanically ventilated patients: a multi-database retrospective cohort study

 

Low-level stable

Ascending

Descending

High-level stable

  

OR (95% CI)

P value

OR (95% CI)

P value

OR(95%CI)

P value

IPTW-logistic

       

 Propensity score IPTW

Reference

1.430 (1.118–1.830)

0.004

1.020(0.813–1.278)

0.866

2.483(1.859–3.317)

< 0.001

 Doubly robust with unbalanced covariablesa

Reference

1.522(1.189–1.948)

< 0.001

1.069(0.849–1.347)

0.568

2.877(2.099–3.945)

< 0.001

 Doubly robust with all covariablesb

Reference

1.473(1.152–1.884)

0.002

1.019(0.817–1.270)

0.869

2.545(1.893–3.422)

< 0.001

IPTW-XGBoost

       

 Propensity score IPTW

Reference

1.532(1.200–1.956)

0.001

0.977(0.771–1.238)

0.676

2.988(2.144–4.165)

< 0.001

 Doubly robust with unbalanced covariablesa

Reference

1.097(1.027–1.172)

< 0.001

0.986(0.940–1.035)

0.849

1.422(1.246–1.623)

< 0.001

 Doubly robust with all covariablesb

Reference

1.500(1.178–1.911)

0.001

0.936(0.750–1.168)

0.556

2.776(1.988–3.875)

< 0.001

  1. aAdjusted for plateau pressure, OSI at baseline, PEEP, NMBAs, APS-III score, PaCO2, vasopressor therapy, age
  2. bAdjusted for plateau pressure, OSI at baseline, PEEP, NMBAs, APS-III score, PaCO2, vasopressor therapy, age, dialysis therapy, ARDS, AKI, BMI, gender, diabetes, tidal volume, ethnicity, HB, COPD, malignancy, HF, CKD
  3. IPTW: inverse probability of treatment weighting; OR: odds ratio; CI: confidence Interval; OSI: oxygen saturation index; NMBAs: neuromuscular blockades; ARDS: acute respiratory distress syndrome; APS-III score: acute physiology III score; AKI: acute kidney injury; BMI: body mass index; HB: hemoglobin; COPD: chronic obstructive pulmonary disease; HF: heart failure; CKD: chronic kidney disease