Table 5 Effects of body weights on the target attainment of critically ill patients receiving CRRT
From: Lacosamide dosing in patients receiving continuous renal replacement therapy
Body weights (kgs) | % Patients not attained the targets (N) | % Patients attained the targets (N) | Unadjusted RR (95% CI) | p value | Adjusted RR (95% CI) | p value |
|---|---|---|---|---|---|---|
< 60 | 42 (828) | 58 (1142) | 0.180 (0.165–0.198) | < .001 | 0.714 (0.412–1.236) | .229 |
60–70 | 17 (384) | 83 (1924) | 0.823 (0.739–0.916) | < .001 | 1.803 (1.036–3.138) | .037 |
71–80 | 7 (147) | 93 (2088) | 2.526 (2.144–2.976) | < .001 | 4.56 (2.583–8.053) | < .001 |
81–90 | 2 (33) | 98 (1545) | 7.972 (5.668–11.210) | < .001 | 14.345 (7.546–27.273) | < .001 |
91–100 | 0 (3) | 100 (968) | 51.405 (16.592–159.266) | < .001 | 97.100 (27.678–340.650) | < .001 |
100–110 | 1.5 (8) | 98 (511) | 9.778 (4.908–19.480) | < .001 | 19.463 (8.086–46.846) | < .001 |
110–120 | 3.4 (8) | 97 (230) | 4.355 (2.200–8.621) | < .001 | 8.925 (3.726–21.376) | < .001 |
120–130 | 12 (13) | 88 (92) | 1.162 (0.697–1.938) | .564 | 2.423 (1.148–5.113) | < .001 |
130–140 | 9 (4) | 91 (42) | 1.656 (0.648–4.228) | .292 | 3.450 (1.167–10.203) | .020 |
> 140 | 30 (9) | 70 (21) | 0.477 (0.276–0.826) | .008 | 1 | .025 |