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Table 1 Demographic and clinical characteristics of study participants (N = 135)

From: Prognostic implication of downregulated exosomal miRNAs in patients with sepsis: a cross-sectional study with bioinformatics analysis

 

Number (%) of patients or median (IQR)

Age, years

66 (58–74)

Sex, male

91 (67.4)

BMI, kg/m2

22.9 (20.6–26.0)

Comorbidity

 

Malignancy

66 (48.9)

Diabetes

41 (30.4)

Chronic obstructive pulmonary disease

16 (11.9)

Chronic kidney disease

10 (7.4)

Cerebrovascular disease

8 (5.9)

Chronic liver disease

8 (5.9)

Congestive heart failure

7 (5.2)

Connective tissue disease

2 (1.5)

Clinical status at ICU admission

 

Need for mechanic ventilation

59 (43.7)

Need for vasopressor support

70 (51.9)

Severity of illness

 

SAPS3 score

55 (47–63)

APACHE II score

24 (20–30)

SOFA score

9 (7–11)

Laboratory findings

 

CRP, mg/dL

12.5 (5.9–24.8)

Lactic acid, mmol/L

2.9 (2.0–4.4)

Procalcitonin, ng/mL

6.06 (0.85–25.18)

IL-6, pg/mL

228 (65–807)

Platelet count, 103/μL

135 (59–214)

Albumin, g/dL

2.9 (2.6–3.2)

Total bilirubin, mg/dL

1.1 (0.7–2.5)

Creatinine, mg/dL

1.3 (0.8–1.9)

  1. IQR interquartile range, BMI body mass index, ICU intensive care unit, SAPS 3 simplified acute physiology score 3, APACHE II acute physiology, and chronic health evaluation II, SOFA sequential organ failure assessment, CRP C-reactive protein, IL-6 interleukin-6