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Table 1 Inclusion and exclusion criteria to select eligible clinical questionsa in this study

From: Comparison of certainty of evidence between the net benefit approach and the traditional GRADE method using the data of Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020

Criteria

Inclusion criteria

1) Certainty of evidence was evaluated using the GRADE

2) Outcomes to be combined for calculating net effect estimate are dichotomous variablesb,c

Exclusion criteria

1) Diagnostic test accuracy or network meta-analysis

2) Only one outcome to be combined for calculating net effect estimate

  1. GRADE, Grading of Recommendations Assessment, Development, and Evaluation
  2. aThe clinical questions were selected from the Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020
  3. bThe net benefit approach cannot be applied to clinical questions with both dichotomous and continuous outcomes
  4. cTT and HO determined the outcomes to be combined to calculate net effect estimate
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Journal of Intensive Care

ISSN: 2052-0492