Table 2 Subgroup analyses according to age, study design, diagnosis and severity of sepsis

1.58 (1.46–1.71)

0.77 (0.67–0.89)

0.62 (0.59–0.65)

1.72 (1.35–2.19)

0.89 (0.68–1.14)

0.77 (0.50–1.18)

1.26 (1.01–1.56)

0.81 (0.73–0.91)

0.72 (0.64–0.80)

1.28 (1.11–1.47)

0.70 (0.43–1.13)

0.85 (0.69–1.05)

1.19 (0.89–1.58)

0.84 (0.65–1.10)

0.83 (0.74–0.94)

1.24 (0.95–1.62)

0.72 (0.62–0.84)

0.63 (0.59–0.66)

1.34 (1.13–1.59)

0.77 (0.69–0.86)

0.72 (0.64–0.82)

1.17 (0.84–1.61)

0.80 (0.61–1.05)

0.79 (0.69–0.91)