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Table 2 Ventilator settings, physiological data, and blood gas analysis in each section

From: Accuracy evaluation of mainstream and sidestream end-tidal carbon dioxide monitoring during noninvasive ventilation: a randomized crossover trial (MASCAT-NIV trial)

 

During SBT

Noninvasive ventilation

P value*

Previous method

Novel method

Ventilation mode

   

1.000

 PSV, n (%)

NA

50 (83.3)

51 (85.0)

 

 CPAP, n (%)

NA

10 (16.7)

9 (15.0)

 

FIO2, median (IQR)

0.3 (0.3–0.4)

0.3 (0.3–0.4)

0.3 (0.3–0.4)

1.000

PEEP, median (IQR), cmH2O

5 (5–5)

4 (4–4)

4 (4–4)

1.000

PS, median (IQR), cmH2O†

5 (5–5)

4 (2–4)

4 (2–4)

1.000

Heart rate, mean (SD), bpm

85.0 (15.5)

85.0 (14.7)

85.5 (15.1)

0.351

Mean blood pressure, mean (SD), mmHg

81.2 (11.6)

82.1 (11.6)

80.5 (11.6)

0.063

Respiratory Rate, mean (SD), breaths /min

15.9 (4.9)

18.2 (5.8)

19.1 (6.1)

0.108

Tidal Volume, mean (SD), mL

528 (157)

469 (130)

474 (122)

0.692

Minute ventilation, mean (SD), L/min

7.9 (2.3)

8.1 (3.2)

8.6 (3.3)

0.084

RSBI, mean (SD)

33.6 (16.1)

43.1 (20.4)

42.9 (17.0)

0.939

Total leakage, mean (SD), L/min

NA

45.1 (11.5)

36.1 (8.3)

 < 0.001

PaO2, median (IQR), mmHg

87.3 (77.5–100.0)

86.2 (76.0–100.5)

89.6 (75.9–97.9)

0.793

P/F ratio, median (IQR)

290 (214–364)

271 (216–335)

280 (211–342)

0.601

PaCO2, mean (SD), mmHg

37.6 (5.7)

38.2 (5.5)

38.4 (5.4)

0.286

PETCO2, mean (SD), mmHg

35.1 (5.8)

32.0 (6.3)

35.7 (5.5)

 < 0.001

pH, mean (SD)

7.43 (0.05)

7.42 (0.05)

7.42 (0.05)

0.610

  1. CPAP, continuous positive airway pressure; FIO2, fraction of inspiratory oxygen; NA, not applicable; PaCO2, arterial partial pressure of carbon dioxide; PaO2, arterial partial pressure of oxygen; PEEP, positive end expiratory pressure; PETCO2, end-tidal partial pressure of carbon dioxide; P/F ratio, ratio of arterial oxygen partial pressure to fractional inspired oxygen; PS, pressure support; PSV, pressure support ventilation; RSBI, rapid shallow breathing index; SBT, spontaneous breathing trial
  2. *Compared measurements in patients using the novel method with the previous method
  3. Among patients who underwent PSV during noninvasive ventilation