Wave 1 (n = 18) | Wave 2 (n = 18) | P | |
---|---|---|---|
Age—years | 66 [61–70] | 70 [61–73] | 0.419 |
Male gender—n (%) | 14 (78) | 15 (83) | > 0.99 |
Body mass index—kg/m2 | 31 [28–36] | 31 [28–36] | 0.567 |
Hypertension—n (%) | 8 (44) | 10 (56) | 0.740 |
Diabetes—n (%) | 5 (63) | 9 (50) | 0.310 |
SAPS II score—points | 39 [33–50] | 37 [31–47] | 0.486 |
SOFA score at Day 1a—points | 8 [6–9] | 5 [2–8] | 0.041 |
Delay between symptoms and ICU admission—days | 6 [4–9] | 9 [7–11] | 0.09 |
Delay between ICU admission and intubation—days | 1 [0–2] | 1 [1, 2] | 0.356 |
Bacterial superinfection at intubation—n (%) | 6 (33) | 3 (17) | 0.440 |
Lowest PaO2/FiO2 ratio during ICU stay—mmHg | 83 [62–112] | 81 [62–100] | 0.784 |
Severity of ARDS—n (%) | 0.460 | ||
Moderate | 6 (33) | 4 (22) | |
Severe | 12 (67) | 14 (78) | |
Duration of invasive mechanical ventilation—days | 29 [18–47] | 12 [8–22] | < 0.01 |
Ventilation acquired pneumoniae—n (%) | 15 (83) | 13 (72) | 0.802 |
Delay between intubation and VAP—days | 13 [8–27] | 7 [5–11] | 0.020 |
Day 28 mortality—n (%) | 5 (28) | 2 (11) | 0.210 |
Day 90 mortality—n (%) | 8 (44) | 3 (17) | 0.150 |