Table 2 Demographic data and main measurements among septic shock patients

Age, mean (SD), year

67.7 (15.4)

70.3 (15.2)

63.9 (15.0)

0.040

Male, No. (%)

62 (62.0)

33 (56.9)

29 (69.0)

0.217

BMI, mean (SD), kg/m²

21.7 (4.2)

21.6 (4.3)

21.7 (4.2)

0.877

APACHE-II score

23.8 (8.9)

25.4 (9.1)

21.7 (8.3)

0.037

Vasoactive inotropic score

103.5 (20.8–174.5)

137.2 (73.4–220.9)

27.7 (0.7–102.5)

< 0.001

MAP, mmHg

80.1 (13.2)

72.9 (9.9)

90.0 (10.6)

<0.001

Respiratory rate, times/min

26.0 (20.0–34.8)

25.0 (20.0–32.0)

29.5 (20.8–37.3)

0.135

Heart rate, beats/min

117.2 (26.8)

117.4 (27.6)

117.0 (26.0)

0.948

Body temperature, °C

37.0 (36.2–38.0)

37.0 (36.3–38.0)

37.0 (36.0–38.0)

0.916

Bloodstream infection

18 (18.0)

9 (15.5)

9 (21.4)

0.448

Pulmonary infection

37 (37.0)

19 (32.8)

18 (42.9)

0.302

Abdominal infection

23 (23.0)

13 (22.4)

10 (23.8)

0.870

Urinary infection

3 (3.0)

3 (5.2)

0 (0.0)

0.135

Infection of biliary tract

7 (7.0)

5 (8.6)

2 (4.8)

0.455

Skin soft-tissue infection

1 (1.0)

1 (1.7)

0 (0.0)

0.392

Other

11 (11.0)

8 (13.8)

3 (7.1)

0.294

Chronic heart disease

17 (17.0)

12 (20.7)

5 (11.9)

0.248

Chronic kidney disease

10 (10.0)

6 (10.3)

4 (9.5)

0.893

Diabetics

12 (12.0)

7 (12.1)

5 (11.9)

0.980

Hypertension

12 (12.0)

6 (10.3)

6 (14.3)

0.549

Mechanical ventilation, No. (%)

95 (95.0)

55 (94.8)

40 (95.2)

0.926

CRRT, No. (%)

59 (59.0)

40 (69.0)

19 (45.2)

0.017

Day-1 total amount, mean (SD), ml^a

3935.2 (1500.9)

4365.6 (1568.3)

3340.8 (1181.4)

0.001

Day-1 output, mean (SD), ml^b

2447.8 (1386.5)

2385.6 (1379.9)

2533.9 (1407.7)

0.600

Day-1 volume, mean (SD), ml^c

1487.3 (1831.0)

1980.0 (1932.3)

806.9 (1444.5)

0.001

Day-7 mortality, No. (%)

34 (34.0)

30 (51.7)

4 (9.5)

<0.001

Day-14 mortality, No. (%)

47 (47.0)

39 (67.2)

8 (19.0)

<0.001

Day-28 mortality, No. (%)

57 (57.0)

43 (74.1)

14 (33.3)

<0.001

ICU mortality, No. (%)

58 (58.0)

43 (74.1)

15 (35.7)

< 0.001

ICU LOS, median (IQR), d

9.0 (5.0–17.8)

8.0 (3.0–13.3)

12.5 (6.8–20.8)

0.018

Hospital mortality, No. (%)

61 (61.0)

44 (75.9)

17 (40.5)

< 0.001

Hospital LOS, median (IQR), d

22.0 (11.0–32.8)

15.5 (6.8–28.0)

23.5 (15.5–40.3)

0.006

CVP, cmH₂O

14.7 (5.9)

16.0 (6.1)

12.9 (5.2)

0.009

GEDI, ml/m²

707.0 (605.5–842.3)

698.0 (599.3–861)

712.0 (616.8–817.5)

0.992

SVRI, dyn.s.cm^-5.m²

2063.7 (792.6)

2119.7 (921.3)

1986.5 (571.1)

0.376

ELWI, ml/kg

9.0 (6.6–14.5)

9.2 (7.0–15.0)

8.2 (6.0–13.6)

0.206

CI, L/min/m²

3.09 (0.98)

2.77 (0.98)

3.55 (0.79)

<0.001

CPI, W/m²

0.55 (0.20)

0.44 (0.16)

0.70 (0.16)

<0.001

LVEF, median (IQR), %

LVEF

60.0 (55.0–64.8)

58.7 (54.0–63.3)

62.0 (59.4–65.3)

0.006

White blood cell, ×10⁹/L

10.8 (6.1–19.1)

12.8 (6.2–21.2)

8.7 (5.8–15.6)

0.180

Neutrophils lymphocytes ratio

21.8 (26.4)

22.7 (27.6)

20.6 (24.9)

0.702

Hemoglobin, g/L

94.6 (24.4)

92.1 (23.8)

98.1 (25.0)

0.229

Platelet, ×10⁹/L

99.0 (41.0–191.5)

72.5 (33.8–186.8)

129.5 (54.8–208.3)

0.051

Total bilirubin, μmol/L

23.5 (13.0–45.5)

35.0 (13.8–55.7)

16.7 (11.0–29.3)

0.005

Albumin, g/L

25.3 (4.8)

24.6 (4.9)

26.4 (4.6)

0.061

Serum creatinine, μmol/L

156.9 (92.4–229.5)

161.2 (95.9–234.7)

125.6 (86.6–222.1)

0.311

Urea, mmol/L

12.0 (8.0–17.9)

11.8 (7.4–19.0)

12.2 (8.1–16.0)

0.810

Calcium ion, mmol/L

1.98 (1.87–2.17)

2.00 (1.89–2.17)

1.97 (1.87–2.18)

0.722

D-dimer, mg/L

5.3 (3.1–10.0)

5.1 (3.2–15.8)

6.2 (2.8–8.4)

0.603

Fibrinogen, g/L

3.6 (1.8)

3.3 (1.7)

4.1 (1.8)

0.023

Procalcitonin, ng/ml

24.4 (3.0–56.7)

31.6 (5.3–58.4)

19.0 (1.0–56.4)

0.336

Lactate, mmol/L

4.8 (2.0–8.9)

5.6 (2.3–12.1)

3.8 (1.9–5.6)

0.006