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Table 5 Univariate and multivariate logistic regression analysis of predictors of short-term mortality among ICU admissions with sepsis

From: Epidemiology and outcomes of sepsis among hospitalizations with systemic lupus erythematosus admitted to the ICU: a population-based cohort study

Variables

Unadjusted odds ratio

p

Adjusted odds ratio

p

(95% CI)

(95% CI)

Age (years)

 18–44

Reference

 

Reference

 

 45–64

1.524 (1.470–1.601)

< 0.0001

1.470 (1.403–1.537)

< 0.0001

 ≥ 65

2.422 (2.237–2.635)

< 0.0001

2.209 (2.185–2.410)

< 0.0001

Gender

    

 Male

Reference

   

 Female

0.690 (0.578–0.824)

< 0.0001

0.829 (0.675–1.018)

0.0738

Race/ethnicity

 White

Reference

 

Reference

 

 Hispanic

0.748 (0.641–0.871)

0.0002

NA

 

 Black

0.672 (0.577–0.783)

< 0.0001

0.848 (0.718–1.003)

0.0548

 Other

0.962 (0.763–1.213)

0.7475

NA

 

Health insurance

 Private

Reference

 

Reference

 

 Medicare

1.251 (0.771–1.029)

0.0849

NA

 

 Medicaid

0.673 (0.543–0.836)

0.0003

NA

 

 No insurance

1.642 (1.586–1.815)

< 0.0001

1.406 (1.075–1.840)

0.0128

 Other

1.004 (0.801–1.258)

0.9672

NA

 

Comorbid conditions

 Chronic lung disease

1.032 (0.904–1.178)

0.6351

NA

 

 Congestive heart failure

1.344 (1.188–1.524)

< 0.0001

NA

 

 Cerebrovascular disease

1.966 (1.643–2.353)

< 0.0001

1.569 (1.265–1.946)

< 0.0001

 Renal disease

0.664 (0.587–0.750)

0.0001

NA

 

 Diabetes

0.678 (0.496–0.927)

0.015

0.725 (0.505–1.042)

0.083

 Malignancy

3.633 (2.880–4.584)

< 0.0001

3.604 (2.725–4.767)

< 0.0001

 Liver disease

2.885 (2.460–3.384)

< 0.0001

1.501 (1.128–1.997)

0.0053

Transfer from another hospital

1.918 (1.604–2.294)

< 0.0001

1.500 (1.216–1.851)

0.0002

Weekend admission

1.004 (0.871–1.158)

0.9472

NA

 

Teaching hospital

1.096 (0.962–1.248)

0.1649

NA

 

Infection site

 Respiratory

Reference

   

 Urinary

0.575 (0.489–0.676)

< 0.0001

0.759 (0.433–0.952)

0.0041

 Abdominal

0.837 (0.675–1.083)

0.1556

NA

 

 Skin and soft tissue

0.702 (0.428–1.150)

0.1603

NA

 

 Devise-related

1.602 (0.873–2.971)

0.573

NA

 

 Other

2.116 (0.905–3.764)

0.9593

NA

 

Type of organ dysfunction

 Respiratory

7.240 (6.265–8.368)

< 0.0001

6.152 (5.243–7.219)

< 0.0001

 Cardiovascular

1.502 (1.284–1.757)

< 0.0001

1.418 (1.172–1.716)

0.0003

 Renal

1.180 (1.027–1.354)

0.0188

1.410 (1.196–1.663)

< 0.0001

 Hepatic

4.958 (4.049–6.070)

< 0.0001

1.895 (1.322–2.715)

0.0005

 Hematological

2.318 (2.039–2.636)

< 0.0001

1.839 (1.573–2.149)

< 0.0001

 Neurological

2.954 (2.570–3.394)

< 0.0001

1.798 (1.520–2.127)

< 0.0001

Year of admission

1.012 (1.976–1.048)

0.5111

NA

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